Panucci had a spell at Chelsea, Festa was at Middlesborough for a bit but as others said Italian players tend not to travel abroad often the only top Italian defender I can think of who played outside of Italy was Cannavaro when he went to Madrid. The Italians are a bit like the English tend not to travel to well and enjoy the comforts of home I think that's partly because the Italian clubs don't mind selling to each other, the only Italian who I think maybe left while still in his prime was Zola when he came to Chelsea there were a few other older guys who came for a bit of a pay day but Zola was the only one still in his prime.
At least someone has seen him play it does sound like Utd are looking at alternatives to Alderwiereld because of the price, I'm actually quite interested to see how Lindelof does at the world cup for Sweden.